Table 3 Loss of milestones
From: Leigh syndrome global patient registry: uniting patients and researchers worldwide
Age when milestone was lost (years) | |||||||
|---|---|---|---|---|---|---|---|
Milestone | Na | Lost | Never achieved | Lost or never achieved | Nb | Mean (SD); Mode | Median (Q1, Q3); Min, Max |
n (%) | n (%) | n (%) | |||||
Walk | 112 | 42 (37.50) | 44 (39.29) | 86 (76.79) | 33 | 3.5 (5.6); 2 | 2.0 (2.0, 3.0); 1, 33 |
Crawl | 114 | 39 (34.21) | 25 (21.93) | 64 (56.14) | 30 | 4.1 (6.5); 2 | 2.0 (1.4, 3.0); 1, 29 |
Sit up | 114 | 40 (35.09) | 18 (15.79) | 58 (50.88) | 34 | 3.1 (4.2); 2 | 2.0 (1.0, 3.0); 1, 24 |
Be toilet trained | 113 | 19 (16.81) | 35 (30.97) | 54 (47.79) | 16 | 3.5 (2.0); 2 | 3.0 (2.0, 5.0); 1, 8 |
Speak whole sentences | 113 | 19 (16.81) | 35 (30.97) | 54 (47.79) | 13 | 3.6 (2.4); 2 | 3.0 (2.0, 4.0); 1, 9 |
Speak 2-word combinations | 98 | 25 (25.51) | 24 (24.49) | 49 (50.00) | 17 | 2.9 (2.3); 2 | 2.0 (2.0, 3.0); 1, 9 |
Swallow | 114 | 34 (29.82) | 6 (5.26) | 40 (35.09) | 28 | 3.6 (3.6); 3 | 3.0 (1.1, 3.5); 0, 17 |
At least one milestone | 116 | 71 (61,21) | 65 (56.03) | 97 (83.62) | |||