Table 2 History of symptoms
From: Leigh syndrome global patient registry: uniting patients and researchers worldwide
Age first experienced symptom (years) | |||||
|---|---|---|---|---|---|
Symptom | Na | Symptom experienced | Nb | Mean (SD); Mode | Median (Q1, Q3); Min, Max |
n (%) | |||||
Hypotonia | 100 | 80 (80.00) | 47 | 1.2 (1.4); 1 | 1.0 (0.4, 1.5); 0, 9 |
Failure to thrive | 97 | 69 (71.13) | 55 | 1.3 (1.2); 1 | 1.0 (0.4, 2.0); 0, 6 |
Nystagmus or strabismus | 105 | 69 (65.71) | 52 | 2.2 (2.5); 1 | 1.5 (0.9, 2.3); 0, 15 |
Seizures | 104 | 46 (44.23) | 32 | 2.9 (4.1); 1 | 1.0 (0.4, 3.0); 0, 18 |
Gastric reflux | 98 | 45 (45.92) | 34 | 1.5 (1.7); 1 | 0.9 (0.3, 2.0); 0, 6 |
Hand tremor | 97 | 44 (45.36) | 35 | 2.9 (2.9); 2 | 2.0 (1.0, 3.0); 0, 16 |
Dystonia | 98 | 40 (40.82) | 30 | 3.3 (3.5); 2 | 2.0 (0.8, 3.0); 0, 16 |
Gastric motility issues | 91 | 31 (34.07) | 24 | 3.7 (6.5); 1 | 1.8 (1.0, 3.0); 0, 30 |
Sleep apnea | 96 | 28 (29.17) | 22 | 2.7 (1.7); 2 | 2.5 (1.7, 4.0); 0, 6 |
Tics | 96 | 17 (17.71) | 15 | 3.6 (2.3); 4 | 3.0 (2.0, 4.0); 0, 9 |