Table 3 The most influential nodes in the mc_GBPN, selected by their TNCS across all centrality measures
Mc_GBPN Index | Node Description | TNCS |
|---|---|---|
0 | • X-linked Adrenoleukodystrophy (X-ALD) • ABCD1 WT Allele, ABC42, AMN, ACOX1, ECK2921, ECK1408 genes • VK-0214 | 4.407 |
12 | • Ataxias, Choreas • SETX, WASF1, GCH1 genes | 5 |
38 | • Absence Epilepsy • CSTB, GABRA1, EC1 genes | 3.986 |
27 | • Amyotrophic Lateral Sclerosis (ALS) • ALS1, ALS2, IGFALS genes • Riluzole, Cannabidiol, Stem Cell Therapy | 5 |
21 | • Parkinson’s Disease • FBXO7, DCTN1, GBA, PARK1, PARK2, PARK5, PARK6, PARK7, PARK8 genes | 4.413 |
14 | • Spastic Paraplegia 10 (SPG10) • KIF5A gene | 3.625 |
22 | • Neurodegeneration with Brain Iron Accumulation 3 (NBIA3) • FTL gene | 5 |
16 | • Rett Syndrome • MECP2 gene | 5 |
2 | • Myoclonus Dystonia (M-D) • SGCE gene | 5 |
17 | • CADASIL and CARASIL Syndromes • NOTCH3, COL4A1, HTRA1 genes • Cerebrolysin, Palm Tocotrienol Complex | 5 |