Table 3 Descriptive statistics for lysosomal enzymes measured in groups 1 (Gaucher Disease Patients) and Group 2 (Metachromatic Leukodystrophy Patients) (Reference range for enzymes are not available in cerebrospinal fluid)
Enzyme | Group | N | Mean | SD | p |
|---|---|---|---|---|---|
Beta-hexosaminidase A | 1 | 5 | 94.8 | 70.0 | |
2 | 4 | 187.5 | 32.2 | 0.063 | |
Beta-hexosaminidase B | 1 | 5 | 43.4 | 41.3 | |
2 | 4 | 20.7 | 8.7 | 0.556 | |
Total Beta-hexosaminidase | 1 | 5 | 112.4 | 57.3 | |
2 | 4 | 208.2 | 34.7 | 0.037 | |
% Beta-hexosaminidase A | 1 | 5 | 56.0 | 49.1 | |
2 | 4 | 90.0 | 4.2 | 0.268 | |
Beta-glucuronidase | 1 | 5 | 4.6 | 3.2 | |
2 | 6 | 1.1 | 0.5 | 0.035 | |
Chitotriosidase | 1 | 5 | 62.0 | 43.7 | |
2 | 6 | 142.9 | 101.3 | 0.082 | |
Alpha-Mannosidase | 1 | 5 | 1.9 | 1.7 | |
2 | 6 | 1.27 | 0.5 | 0.713 |