Table 4 Results for the main effect (full cohort) and effect modification (interaction) from the zero-inflated Poisson model for any morbidity (yes/no, zero-inflation model) and number of morbidities (count model) for adults with spinal muscular atrophy (SMA) compared to matched adults without SMA (w/o SMA).

OR (95% CI)

IRR (95% CI)

Full cohort*

Females

SMA vs. w/o SMA

0.26 (0.20, 0.33)

2.11 (2.06, 2.16)

Males

SMA vs. w/o SMA

0.16 (0.12, 0.22)

2.15 (2.10, 2.21)

Age interaction

Females

SMA vs. w/o SMA

18–39 years

0.23 (0.16, 0.33)

3.33 (3.07, 3.60)

40–54 years

0.34 (0.23, 0.50)

3.00 (2.82, 3.20)

55–64 years

0.14 (0.06, 0.34)

2.24 (2.10, 2.38)

65–74 years

0.71 (0.46, 1.09)

2.00 (1.91, 2.09)

≥75 years

**

1.75 (1.67, 1.83)

Males

SMA vs. w/o SMA

18–39 years

0.14 (0.08, 0.22)

2.91 (2.61, 3.24)

40–54 years

0.20 (0.13, 0.30)

2.83 (2.66, 3.02)

55–64 years

0.23 (0.13, 0.41)

2.35 (2.23, 2.49)

65–74 years

0.37 (0.22, 0.61)

2.13 (2.04, 2.22)

≥75 years

**

1.72 (1.63, 1.81)