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Table 2 Association clusters of proteins amyloid-β and tau and FA

From: Neurodegeneration or dysfunction in Phelan-McDermid syndrome? A multimodal approach with CSF and computational MRI

No.

MNI (x/y/z)

size / mm³

C / p

anatomical localization

correlation FA and amyloid-ß

1

-22 / -48 / 14

340

0.78 / 0.0001

splenium / posterior part of the corpus callosum

correlation FA and tau

2

-30/-19/29

2420

-0.76 / 0.0002

left corticospinal tract

3

15/-4/46

1663

-0.77 / 0.0001

right frontal lobe

4

24/13/35

1272

-0.76 / 0.0002

right frontal lobe

5

30/-22/37

877

-0.78 / 0.0001

right parietal lobe

6

-17/-51/56

690

-0.72 / 0.0005

left corticospinal tract

7

18/-13/13

533

-0.67 / 0.002

right corticospinal tract

8

-38/-54/18

466

-0.60 / 0.007

left parietal lobe

9

21/14/40

378

-0.68 / 0.001

left frontal lobe

10

22/34/20

294

-0.72 / 0.0005

left frontal lobe