Table 4 EBV-DNA copies in sorted T, B, and NK cells before and after sintilimab treatment
EBV-DNA (copies/106 cells) | Case 1 | Case 2 | Case 3 | |||
|---|---|---|---|---|---|---|
Before | After 12 cycles | Before | After 4 cycles | Before | After 7 cycles | |
CD3+CD4+ T cells | 7.7 × 105 | 2.9 × 104 | 3.0 × 104 | 1.0 × 104 | – | – |
CD3+CD8+ T cells | 1.1 × 105 | 7.0 × 102 | 3.5 × 104 | 2.2 × 104 | – | – |
CD3−CD19+ B cells | 1.2 × 104 | 1.8 × 103 | 2.3 × 104 | 1.1 × 104 | 6.5 × 105 | 1.6 × 105 |
CD56+ NK cells | 2.7 × 106 | 5.4 × 104 | 5.4 × 104 | 1.4 × 104 | 1.8 × 104 | – |