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Table 1 Baseline characteristics before sintilimab treatment

From: Sintilimab treatment for chronic active Epstein–Barr virus infection and Epstein–Barr virus-associated hemophagocytic lymphohistiocytosis in children

Case

Sex

Age (m)

Weight (kg)

Clinical manifestation

Disease duration

Primary treatment

Diagnosis

1

M

74

16

Intermittent fever

Hepatosplenomegaly

liver function abnormalities

lymphadenopathy

More than 4 years

Antiviral drugs

IVIG

Methylprednisolone

CAEBV

2

F

150

26.7

Intermittent fever

Intermittent skin rash

Oral ulcer

lymphadenopathy

More than 6 years

Antiviral drugs

CAEBV

3

M

50

15.5

Intermittent fever

Intermittent skin rash

Mild abdominal pain

lymphadenopathy

More than 1 month

Antiviral drugs

IVIG

Methylprednisolone pulse

EBV-HLH

  1. IVIG Intravenous immunoglobulin, CAEBV Chronic active Epstein–Barr virus infection, EBV-HLH Epstein–Barr virus-related hemophagocytic lymphohistiocytosis