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Table 1 Baseline characteristics of the cohort (n = 101)

From: Analysis of the genetic contribution to thoracic aortic aneurysm or dissection in a prospective cohort of patients with familial and sporadic cases in East China

Clinical characteristics of the cohort

Mean ± SD or No.(%) patients

Age (years)

57 ± 14 [13–80]

< 50 years at TAAD onset

29(28.7)

≥ 50 years at TAAD onset

72(71.3)

Sex

 

Male

82(81.2)

Female

19(18.8)

Thoracic aortic disease

 

Aortic aneurysm

7(6.9)

Acute aortic syndrome

94(93.1)

Aortic dissection

91(88.1)

Stanford Type A

60(59.4)

Stanford Type B

29(28.7)

Aortic dissection and aneurysm

58(57.4)

Intramural haematoma

2(2.0)

Penetrating aortic ulcer

3(3.0)

Suspected Syndrome

2(0.2)

Aortic diameter

40.3(7.7)

Z score ≥ 2

46(45.5)

-2 < Z score < 2

49(48.5)

Z score≤-2

2(0.02)

Risk factors and comorbidities:

 

Proven positive family history of aortic disease

1(0.1)

Marfan syndrome

2(0.2)

Hypertension

73(72.3)

Smoke history

32(31.7)

Hyperlipidaemia

49(48.5)

Diabetes

51(49.5)

Bicuspid valve

1(0.1)

Coronary artery disease

1(0.1)

Hypothyroidism

0(0.0)

Gastroesophageal reflux disease

0(0.0)

Chronic obstructive pulmonary disease

0(0.0)