Fig. 1

Summary of sequencing results. (A) Numbers of all variants for each gene and percentages of P/LP variants for each gene in the cohort are shown. Impact of age at diagnosis (B, C), blood pressure (D) and arotic diameter (E) on variant category in the whole cohort. Abbreviations: P/LP - pathogenic or likely pathogenic; VUS - variant of uncertain significance; NV/LB – no variant or likely benign