Table 1 Sociodemographic and dietary profiles by diagnosis groupa
From: Total choline intake and working memory performance in adults with phenylketonuria
|  | PKU (n = 40) | Non-PKU (n = 40) | p-valueb |
|---|---|---|---|
Female, n (%) | 29.0 (72.5) | 29.0 (72.5) | 1.00 |
Age (years) | 25.0 (21.0, 30.5) | 26.0 (21.0, 30.5) | 0.70 |
Education (years) | 15.5 (14.0, 16.5) | 16.0 (14.5, 17.0) | 0.31 |
Intellectual ability (Matrix Reasoning Score) | 11.0 (8.5, 13.0) | 12.5 (10.5, 14.0) | 0.03 |
BMI (kg/m2) | 26.7 (23.0, 29.6) | 23.7 (22.0, 27.1) | 0.07 |
Total Energy (kcal/d) | 1902.2 (1548.4, 2270.6) | 1938.7 (1527.1, 2162.0) | 0.78 |
Total Protein Intake (g/d) | 74.1 (60.3, 89.5) | 75.0 (61.5, 95.5) | 0.39 |
Medical Food Protein (g/d) | 48.9 (29.1, 66.0) | – | – |
Intact Protein (g/d) | 22.4 (15.9, 34.6) | – | – |
Total Fat (g/d) | 60.7 (50.6, 82.3) | 78.0 (58.2, 91.2) | 0.04 |
Total Choline (mg/d) | 262.4 (188.7, 556.1) | 315.8 (237.0, 418.4) | 0.53 |
Total Vitamin B12 (mcg/d) | 6.1 (3.3, 11.4) | 5.5 (2.8, 8.4) | 0.35 |
Total Vitamin B6 (mg/d) | 3.3 (2.0, 4.0) | 2.1 (1.5, 3.4) | 0.02 |
Total Folate (mcg DFE/d) | 1166.8 (815.9, 1479.1) | 547.7 (394.1, 738.0) |  < 0.0001 |
Total Methionine + Cysteine (mg/d) | 2169.3 (1643.2, 2925.5) | 2725.3 (2170.0, 3525.2) | 0.01 |
Most Recent Phe (µmol/L) | 362.4 (254.5, 585.9) | – | – |
Sapropterin Dihydrochloride Treatment, n (%) | 22.0 (27.5) | – | – |
PKU Severity, n (%)c |  | – | – |
Classical | 4 (10.0) | – | – |
Moderate | 20 (50.0) | – | – |
Mild | 16 (40.0) | – | – |