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Table 3 Hemoglobin concentration and anemia prevalence by thalassemia/hemoglobinopathy status among women and children in Sylhet, Bangladesh

From: Thalassemia and hemoglobinopathy prevalence in a community-based sample in Sylhet, Bangladesh

Characteristics

Non-pregnant women

Pregnant women

Children (6–37 months)

n

Hemoglobin (g/dl)

Anemiaa

n

Hemoglobin (g/dl)

Anemiaa

n

Hemoglobin (g/dl)

Anemiaa

Mean (SD)

Freq. (%)

Mean (SD)

Freq. (%)

Mean (SD)

Freq. (%)

Total population

768

12.4 (1.2)

244 (31.7)

132

11.5 (1.2)

31 (23.5)

395

10.9 (1.3)

195 (49.4)

Any inherited blood disorders

87

12.1 (1.2)

37 (42.5)

15

10.8 (1.4)

6 (40.0)

41

10.5 (1.3)

25 (61.0)

Alpha thalassemia

 Any

53

12.2 (1.3)

21 (39.6)

9

11.2 (1.3)

3 (33.3)

21

10.8 (1.2)

10 (47.6)

 Minima (aa/−a)

51

12.2 (1.3)

20 (39.2)

8

11.4 (1.3)

2 (25.0)

21

10.8 (1.2)

10 (47.6)

  a3.7deletion

48

12.2 (1.3)

18 (37.5)

8

11.4 (1.3)

2 (25.0)

19

10.8 (1.2)

9 (47.4)

  a4.2deletion

3

11.6 (0.8)

2 (66.7)

0

2

10.6 (1.3)

1 (50.0)

 Minor (aa/− or a−/a−)

         

  a3.7deletions

1

11

1 (100.0)

1

9.8

1 (100.0)

0

Hemoglobin Constant Spring

1

13.3

0 (0.0)

0

0

Triplicate alpha-globin genes (> 5)

20

12.7 (1.3)

7 (35.0)

3

12.8 (0.4)

0 (0.0)

14

10.7 (1.1)

7 (50.0)

 aaaanti3.7

18

12.7 (1.3)

6 (33.3)

3

12.8 (0.4)

0 (0.0)

14

10.7 (1.1)

7 (50.0)

 aaaanti4.2

1

12.8

0 (0.0)

0

0

 Unknown

1

11.2

1 (100.0)

0

0

Beta thalassemia

 Minor (HbA2 < 3.5%)

13

11.4 (1.1)

9 (69.2)

2

9.1 (0.4)

2 (100.0)

9

10.5 (1.3)

7 (77.8)

Hemoglobin E

23

12.1 (1.1)

8 (34.8)

4

10.8 (1.5)

1 (25.0)

7

10.4 (0.9)

5 (71.4)

Hemoglobin D

1

13.8 (0.0)

0 (0.0)

0

2

11.3 (0.7)

1 (50.0)

Hemoglobin S

1

13.7 (0.0)

0 (0.0)

0

0

Hemoglobin X (unable to identify)

0

0 (0.0)

0 (0.0)

0

5

9.3 (2.0)

4 (80.0)

  1. aWe used the following anemia cut-offs: non-pregnant women (mild: Hb 11–11.9 g/dL; moderate: 8.0–10.9 g/dL; severe: Hb < 8.0 g/dL), pregnant women in the first and third trimester (mild: Hb 10–10.9 g/dL; moderate: 7.0–9.9 g/dL; severe: Hb < 7.0 g/dL), pregnant women in the second trimester (mild: Hb 9.5–10.4 g/dL; moderate: 6.5–9.4 g/dL; severe: Hb < 6.5 g/dL), and children (mild: Hb 10–10.9 g/dL; moderate: 7.0–9.9 g/dL; severe: Hb < 7.0 g/dL)