Table 2 Thalassemia and hemoglobinopathy prevalence including genetic deletions among women and children in Sylhet, Bangladesh
From: Thalassemia and hemoglobinopathy prevalence in a community-based sample in Sylhet, Bangladesh
Characteristics | Women | Children | ||
|---|---|---|---|---|
n = 900 | n = 395 | |||
freq | % | freq | % | |
Any inherited blood disorders | 102 | 11.3 | 41 | 10.4 |
Alpha thalassemia | ||||
Any | 62 | 6.9 | 21 | 5.3 |
Minima (aa/−a) | 59 | 6.6 | 21 | 5.3 |
a37deletion | 56 | 6.2 | 19 | 4.8 |
a42deletion | 3 | 0.3 | 2 | 0.5 |
Minor (aa/− or a−/a−) | 2 | 0.2 | 0 | 0.0 |
a37deletions | 2 | 0.2 | 0 | 0.0 |
Intermedia/Major | 0 | 0.0 | 0 | 0.0 |
Hemoglobin Constant Spring | 1 | 0.1 | 0 | 0.0 |
Triplicate alpha globin genes (> 5) | 23 | 2.6 | 14 | 3.5 |
anti3.7aaa | 21 | 2.3 | 14 | 3.5 |
anti4.2aaa | 1 | 0.1 | 0 | 0.0 |
Unknown | 1 | 0.1 | 0 | 0.0 |
Beta thalassemia | ||||
Minor (HbA2 < 3.5%) | 15 | 1.7 | 9 | 2.3 |
Intermedia/Major | 0 | 0.0 | 0 | 0.0 |
Structural hemoglobin variants | ||||
Hemoglobin E | 27 | 3.0 | 7 | 1.8 |
Hemoglobin D | 1 | 0.1 | 2 | 0.5 |
Hemogobin S | 1 | 0.1 | 0 | 0.0 |
Hemoglobin X (unable to identify) | 0 | 0.0 | 5 | 1.3 |