Fig. 5
From: Composite endpoints, including patient reported outcomes, in rare diseases
Three examples of pairwise comparisons of a composite prioritized GPC, with 40% reduction in blister prioritized over the difference in QoL. The pairwise comparison is initiated on the blister outcome. If a subject with a better outcome is assigned (example 1) the QoL outcome is not evaluated. Only when the better outcome cannot be decided on the blister outcome (example 2 and 3) the QoL outcome is compared. If both subjects have equal values in each outcome, the pair is considered a tie (example 3). T= Experimental treatment and C= Control treatment