Table 3 Wash out times for different DMTs
DMT | Wash-out time |
|---|---|
GA | not necessary |
IFN-beta | not necessary |
DMF | not necessary, but normalization of lymphopenia or trend of normalization is recommended |
teriflunomide | necessary, can be shortened by cholestyramine |
fingolimod | ≥ 4 weeks (but not exceeding 8 weeks) |
natalizumab | ≥ 4–8 weeks (but not exceeding 8 weeks) |
alemtuzumab/cladribine | ≥ 6–12 months |
ocrelizumab/ofatumumab/rituximab | ≥ 3–6 months |