Fig. 5

An example of a personalized prediction of the driving capability of an Enroll-HD participant. The blue line indicates the clinical assessment and the orange line indicates the assessment of the ML model. The dashed orange line indicates a prediction over a future time point (time point 5) for this particular individual. The two distributions, clinical assessment and model assessment, do not align at time point 4, which indicates that a patient might have been wrongly assessed by the clinic at that time point, as the model predicted a value around 0.6