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Table 4 Codes in symptoms prior to diagnosis

From: “Because it is a rare disease…it needs to be brought to attention that there are things out of the norm”: a qualitative study of patient and physician experiences of Wilson disease diagnosis and management in the US

Subtheme: Symptoms prior to diagnosis

Physical/Biological

Neurological

Emotional/Psychological

• Liver issues

• Fatigue or tiredness

• Eye problems

• Abnormal blood test results

• Pain or bodily discomfort

• Vomiting

• Inconsistent menstrual cycle

• Nosebleeds

• Fever

• Skin discoloration/jaundice

• Eye problems

• Swelling

• Tremors

• Drooling

• Dysphagia

• Poor memory

• Coordination or motor skills

• Cognitive

• Balance or gait

• Speech problems

• Dizziness

• Weakness

• Affective disorders

• Managing emotions

• Other psychological issues