Fig. 2

Distribution by pharmacologic classes of aspartame containing drugs with a high or medium Phe intake in children. The daily Phe intake of each drug was calculated for a use at conventional posology according to age and weight. We considered that the complete metabolism of 1 g of aspartame results into an equimolar amount of 0.56 g of Phe. High and medium Phe intakes were defined as > 40 mg/d and between 10 and 40 mg/d, respectively. The different drugs were distributed according to the ATC classification available on the WHO website (see “Methods” section for details). The number of drugs for each condition is noted on the graph