Table 2 Patients’ clinical features and comparison between patients with or without GD
From: GAU-PED study for early diagnosis of Gaucher disease in children with splenomegaly and cytopenia
|  | Total number of patients (n = 154) | Gaucher patients (n = 14) | Non-Gaucher patients (n = 140) | P value |
|---|---|---|---|---|
Gender | ||||
 Female | 47 (30.5%) | 6 (42.9%) | 41 (29.3%) |  |
 Male | 107 (69.5%) | 8 (57.1%) | 99 (70.7%) |  |
Age (yrs), mean ± SD | 10.1 ± 5.5 | 10.8 ± 5.3 | 10 ± 5.5 | 0.61 |
Hepatomegaly | 47 (30.5%) | 11 (78.6%) | 36 (25.7%) |  < 0.01 |
Thrombocytopenia | 86 (55.8%) | 12 (85.7%) | 74 (52.9%) |  < 0.05 |
Anemia | 39 (25.3%) | 10 (71.4%) | 29 (20.7%) |  < 0.01 |
Hyperferritinemia | 8 (5.2%) | 2 (14.3%) | 6 (4.3%) | 0.26 |
Bone pain | 21 (13.6%) | 3 (21.4%) | 18 (12.9%) | 0.41 |
Growth delay or deceleration | 15 (9.7%) | 5 (35.7%) | 10 (7.1%) |  < 0.05 |
Strabismus and/or oculomotor apraxia | 3 (1.9%) | 1 (7.1%) | 2 (1.4%) | 0.25 |