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Table 1 Study population characteristics and clinical findings (dichotomous and categorical variables)

From: Oral findings in patients with cartilage-hair hypoplasia - cross-sectional observational study

 

Individuals with CHH

n = 23

Controls

n = 46

Difference between groups

p value

Gender (male/female)

9/14 (39/61%)

17/29 (37/63%)

0.861#

Age mean (range) in years

40(5–70)

36(5–76)

0.321##

Children’s CHH growth percentile*

< 10

10–25

50

1

1

1

  

Adult height (cm)

< 115

4

  

115–130

9

  

> 130

6

40

 

Unknown

1

  

Smoking (yes)

4 (17%)

3 (11%)

0.159#

Oral mucosal lesions (yes)

7 (30%)

4 (9%)

0.036#

TMD (yes)

4 (17%)

7 (15%)

0.809#

Oral fluid aMMP-8 > 20 ng/ml**

9/20 (45%)

18/40 (45%)

1.0#

Decay in deciduous dentition

1/3

0/6

 

Profile

convex

normal

concave

9

13

0

27

19

0

 

Angle classification of occlusion

I

II

III

16

7

0

31

14

1

0.709#

Overjet median (range) in mm

3(-3.5–8)

3(0–11)

 

Overbite median(range) in mm

2(-2–6)

2(-3–8)

 
  1. CHH Cartilage-hair-hypoplasia
  2. Controls Individuals without CHH
  3. * Reference values percentile for height vs. age: Mäkitie et al.[47]
  4. TMD Temporomandibular joint dysfunction
  5. ** Periosafe® test result positive by visual estimation in individuals with permanent dentition
  6. # Chi-Square test
  7. ## Mann-Whitney U-test