Fig. 1
From: Novel pathogenic NPR2 variants in short stature patients and the therapeutic response to rhGH
Growth chart of the three patients with heterozygous NPR2 variants with the rhGH therapies. Height and weight standardized growth charts for Chinese children and adolescents aged 0 to 18 years [36]. The black dots represent records. (A) Height and weight trends of patient 1 during rhGH treatment. (B) Height and weight trends of patient 2 during rhGH treatment. (C) Height and weight trends of patient 3 from 2 years old to 9.5 years old. (D) rhGH treatment response in the three patients with NPR2 gene variants