From: The evolution of the mitochondrial disease diagnostic odyssey
N | Median | Interquartile Range | Mean (SD) | |
---|---|---|---|---|
A Medians and means for age at onset of first symptoms of mitochondrial disease, age at diagnosis, and TOD | ||||
Age at onset | 209 | 14.5 | 37.8 | 20.1 (20.3) |
Age at diagnosis | 198 | 30.2 | 43.1 | 29.7 (22.0) |
Time from onset to diagnosisa | 198 | 4.2 | 11.3 | 9.9 (13.0) |
B TOD by dichotomized age at symptom onset (N = 198) | p = 0.07b | |||
< 2 | 68 | 2.9 | 8.1 | 9.4 (15.0) |
≥ 2 | 130 | 5.8 | 11.6 | 10.2 (11.6) |
C TOD by trichotomized age at onset (N = 198) | p = 0.09c | |||
< 2 | 68 | 2.9 | 8.1 | 9.4 (15.0) |
2–< 12 | 23 | 5.3 | 23.8 | 15.8 (17.6) |
≥ 12 | 107 | 5.8 | 10.6 | 8.9 (9.9) |
D TOD by clinical syndrome of first symptoms (N = 182)d | p = 0.24b | |||
Classice | 65 | 4.0 | 10.6 | 8.3 (11.2) |
Non-classic | 117 | 4.1 | 11.3 | 9.9 (13.1) |