Skip to main content

Table 7 Clinical factors associated with poor treatment outcomes in patients with CNS actinomycosis

From: The epidemiology, clinical presentation and treatment outcomes in CNS actinomycosis: a systematic review of reported cases

Variable

Univariate analysis

Multivariate analysis

P value

Crude OR (95% CI)

P value

Crude OR (95% CI)

Age ≥ 65 (years)

0.041

3.1, (1.2–11.69)

0.414

1.6, (0.32–4.8)

Comorbidities

0.368

1.2, (0.38–4.0)

  

Immunodeficient state

0.10

2.5, (0.61–10.75)

0.293

1.8, (0.76–5.8)

Fever

0.179

0.54, (0.15–1.89)

  

Multiple brain abscess

0.401

1.18, (0.23–5.90)

  

Disseminated disease

0.153

2.2, (0.56–7.2)

  

Combination antibiotics

0.155

0.48, (0.12–1.87)

  

Surgery

 < 0.001

0.028, (0.003–0.23)

0.039

0.14, (0.04–0.28)

  1. OR = Odds ratio, CI = Confidence interval, p value < 0.05 considered significant