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Table 6 The association of various antibiotic regimen and treatment duration with outcome in CNS actinomycosis

From: The epidemiology, clinical presentation and treatment outcomes in CNS actinomycosis: a systematic review of reported cases

Variables

Single antibiotic

Combination antibiotic regimen

p value

Mortality

3/43 (6.9%)

5/61 (8.2%)

0.56

Neurological sequelae

10/32 (31.2%)

5/43 (11.6%)

0.03

 

Penicillin based regimen

Ceftriaxone based regimen

 

Mortality

2/45 (4.4%)

1/27 (3.7%)

0.60

Neurological sequelae

6/33 (18.2%)

3/27 (11.1%)

0.34

 

Antibiotic duration ≤ 3 months

Antibiotic duration > 3 months

 

Neurological sequelae

11/38 (28.9%)

5/43 (11.6%)

0.04