Table 4 Radiological and laboratory diagnosis of CNS actinomycosis
CNS imaging/diagnostic procedures | N (%) |
|---|---|
Brain Abscess | 65/118 (55.1) |
Single | 49/65 (75.4) |
Multiple | 16/65 (24.6) |
Abscess locationa | |
Frontal | 32 (39.5) |
Parietal | 23 (28.4) |
Temporal | 11 (13.6) |
Occipital | 9 (11.1) |
Cerebellar | 6 (7.4) |
Leptomeningeal enhancement | 26 (22) |
Subdural empyema | 17 (14.4) |
Cerebral venous thrombosis/septic emboli/infarct | 20 (16.9) |
Spinal cord involvement (abscess)b | 19 (16.1) |
Hydrocephalus/Ventriculitis | 5 (4.2) |
Culture positive | 63 (53.4) |
Source | |
Brain abscess aspiration | 36/65 (55.4) |
CSF culture | 11/65 (16.9) |
Blood culture | 4 /65 (6.1) |
Other tissuec | 4/65 (6.1) |
Culture site not specified | 8/65 (12.2) |
CSF analysis | |
Neutrophilic pleocytosis | 13/19 (68.4) |
Median total leukocyte counts, (IQR) | 548.5 (133–1380) |
Median CSF protein, mg/dl, (IQR) | 112 (68.3–214.3) |
Median CSF Glucose, mg/dl, (IQR) | 40 (26–54) |