Achondroplasia natural history study (CLARITY): 60-year experience in orthopedic surgery from four skeletal dysplasia centers

Table 5 Risk factors for repeat orthopaedic surgery

	Repeat spine surgery		Repeat lower extremity surgery
	OR (95% CI)	p	OR (95% CI)	p
Age at first surgery	1.01 (0.99–1.03)	0.507	0.98 (0.95–1.01)	0.142
Gender (male:female)	1.03 (0.55–1.94)	0.927	1.13 (0.69–1.87)	0.614
CMD	2.54 (1.23–5.64)	0.016	0.64 (0.35–1.17)	0.143
Hydrocephalus requiring shunt	1.66 (0.65–4.80)	0.314	0.74 (0.35–1.64)	0.450
CMD and hydrocephalus requiring shunt	2.40 (0.74–10.8)	0.185	0.99 (0.40–2.67)	0.983
OSA on CPAP	1.42 (0.90–2.24)	0.13	1.32 (0.90–1.93)	0.16
Prior lower extremity surgery	1.39 (0.71–2.78)	0.346
Prior spine surgery			0.53 (0.30–0.97)	0.037
Height	1.02 (1.01–1.04)	0.001	0.99 (0.98–1.00)	0.094
Weight	1.05 (1.02–1.10)	0.007	0.99 (0.97–1.01)	0.435
OFC	1.07 (1.01–1.13)	0.019	1.00 (0.97–1.03)	0.838

ISSN: 1750-1172