Fig. 1From: Achondroplasia natural history study (CLARITY): 60-year experience in orthopedic surgery from four skeletal dysplasia centersKaplan Meier curve of patients undergoing any orthopaedic, lower extremity or spine surgery by age. These data represent cumulative probability of a surgery (y-axis) as a function of age (x-axis). At 10Â years of age, 19.0% of patients had an orthopaedic procedure with 16.2% having a lower extremity surgery and 3.4% with spine surgery. At 20Â years of age, 41.8% of patients had an orthopaedic procedure with 32.0% having a lower extremity surgery and 14.4% with spine surgery. At 40Â years of age, 60.9% had an orthopaedic procedure with 35.3% having a lower extremity surgery and 39.6% with spine surgery. At 60Â years of age, 85.3% had an orthopaedic procedure with 52.6% having lower extremity surgery and 68.9% with spine surgery. At 80Â years of age, 95.1% had an orthopaedic procedure with 52.6% having lower extremity surgery and 89.6% with spine surgeryBack to article page