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Table 5 A total of fifteen pathways contain a high amount of biomarkers for both assays, with at best 46 markers included in one individual pathway model

From: Extending inherited metabolic disorder diagnostics with biomarker interaction visualizations

Pathway ID

Title of pathway*

ChEBI IDs In PW

WP3604

Biochemical pathways: part I%

46

WP4042

Nucleobase catabolism%

21

WP4225

Pyrimidine metabolism and related diseases

18

WP1936

Transport of inorganic cations/anions and amino acids/oligopeptides%

17

WP4584

Biomarkers for pyrimidine metabolism disorders

17

WP1935

Transport of bile salts and organic acids, metal ions and amine compounds%

17

WP3925

Amino acid metabolism

15

WP4224

Purine metabolism and related disorders

14

WP4082

Nucleotide salvage%

14

WP1938

tRNA aminoacylation%

13

WP1937

Transport of vitamins, nucleosides, and related molecules%

12

WP4792

Purine metabolism

12

WP4595

Urea cycle and associated pathways

11

WP4022

Pyrimidine metabolism

10

WP4583

Biomarkers for urea cycle disorders

10

  1. Medical-Ethical Review * : % indicates which pathways were not found in the top three relevant pathways for any patient