Table 4 Amount of unique DataNodes (proteins, metabolites) and disorders captured by each pathway model
From: Extending inherited metabolic disorder diagnostics with biomarker interaction visualizations
Model name | PWM ID | #Proteins (HGNC) | #Metabolites (ChEBI) | #Interactions (Rhea) | #Disorders (OMIM) |
|---|---|---|---|---|---|
Purine metabolism and related disorders | WP4224 | 22 | 61 | 51 | 17 |
Pyrimidine metabolism and related diseases | WP4225 | 17 | 41 | 33 | 15 |
Urea cycle and related diseases | WP4571 | 9 | 16 | 7 | 9 |
Urea cycle and associated pathways | WP4595 | 24 | 35 | 23 | 12 |
Biomarkers for urea cycle disorders | WP4583 | 12 | 29 | 10 | – |
Biomarkers for pyrimidine metabolism disorders | WP4584 | 15 | 39 | 29 | – |