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Table 4 Intracellular platelet signaling

From: Novel SLFN14 mutation associated with macrothrombocytopenia in a patient with severe haemorrhagic syndrome

 

Calcium-patient, nM

Calcium-norm, nM

Fibrinogen-patient, %

Fibrinogen-norm, %

Preactivation

10 ± 4

19 ± 15

3.3 ± 1.0

3.3 ± 1.3

ADP, 4 µM

154

69 ± 32

6.3

8.9 ± 4.7

CRP-XL, 0.5 µg/ml

10.08

56 ± 30

9.1

2.1 ± 1.8

TRAP-6, 2 µM

35.97

180 ± 44

14.2

8.8 ± 3.7