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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Novel SLFN14 mutation associated with macrothrombocytopenia in a patient with severe haemorrhagic syndrome

Fig. 3

Light transmission aggregometry and growth of thrombi in the flow chamber. Panel A shows platelet aggregation curves from a healthy volunteer. Panel B shows the patient’s aggregation alteration with all agonists except agglutination/aggregation with ristocetin. The number of thrombus foci was reduced in the patient compared to the control (panels D and C, respectively, microphotographs at ×20 magnification). The length of the thrombi in the patient was comparable to the control (panels F and E, respectively, microphotographs at ×100 magnification).

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172