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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Multisystem ALK-positive histiocytosis: a multi-case study and literature review

Fig. 1

Radiological and pathological features of case 1. A Chest CT showed a large mass in the upper lobe of the right lung, involving the right anterior superior mediastinum, hilar, and hilar lymph nodes. B, C The mediastinal nodule exhibited large polymorphic histiocytes with frequent Touton giant cells. D The tumor cells were positive for CD68. E The tumor cells were positive for ALK1. F ALK-FISH (a break-apart probe) was positive. (Original magnification × 200 [B, C, D, E]; × 1000 [F])

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