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Table 3 Distribution of the ABCB4 c.711A > T genotypes in patients with and without cirrhosis

From: A common variant in the hepatobiliary phospholipid transporter ABCB4 modulates liver injury in PBC but not in PSC: prospective analysis in 867 patients

  

Genotype counts

Test for association

[TT]

[AT]

[AA]

OR

χ2

P

PBC (Szczecin)

Patients with cirrhosis

2 (3%)

15 (20%)

57 (77%)

1.84

5.00

0.025

Patients without cirrhosis

9 (8%)

37 (30%)

76 (62%)

PSC (Szczecin)

Patients with cirrhosis

1 (2%)

19 (36%)

33 (62%)

  

NS

Patients without cirrhosis

4 (5%)

25 (30%)

53 (65%)

PBC (Warsaw)

Patients with cirrhosis

3 (3%)

25 (22%)

86 (75%)

1.53

4.28

0.039

Patients without cirrhosis

5 (3%)

50 (34%)

91 (62%)

PSC (Warsaw)

Patients with cirrhosis

3 (3%)

21 (23%)

68 (74%)

  

NS

Patients without cirrhosis

7 (4%)

50 (27%)

127 (69%)

  1. Analyses were performed using Armitage's trend test. Abbreviations: please see legend Table 1; NS not significant, OR odds ratio
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172