Table 3 Peak areas and peak heights of analyte and IS referred to the calibrators and to the QCs with the corresponding calculated concentration. CAL calibrators. NA not available. Cps counts per second calculated concentration and accuracy

1°CALIBRATION CURVE R² = 0.9998 y = 0.00532x-0.00858

CAL 0

0.0

0.0

1.77*10⁶

6.44*10⁵

0.0

0.0

CAL1

2.45*10⁴

7.89*10³

4.91*10⁶

1.91*10⁶

2.5

2.67

CAL2

4.43*10⁴

1.86*10⁴

2.43*10⁶

9.07*10⁵

5

5.15

CAL3

1.55*10⁵

5.87*10⁴

3.45*10⁶

1.39*10⁶

10

9.94

CAL4

2.80*10⁵

1.05*10⁵

2.30*10⁶

8.70*10⁵

25

24.5

CAL5

6.17*10⁵

2.33*10⁵

2.38*10⁶

8.96*10⁵

50

50.2

QC I

7.52*10⁴

2.75*10⁴

6.04*10⁶

2.33*10⁶

4

4.06

QC II

1.96*10⁵

6.86*10⁴

9.81*10⁵

3.98*10⁵

40

39.1

2° CALIBRATION CURVE R² = 0.9995 y = 0.00475x + 0.00569

CAL 0

0.0

0.0

7.97*10⁵

2.51*10⁵

0.0

0.0

CAL1

4.92*10⁴

1.58*10⁴

2.73*10⁶

9.18*10⁵

2.5

2.60

CAL2

3.03*10⁴

1.20*10⁴

9.47*10⁵

3.14*10⁵

5

5.52

CAL3

1.16*10⁵

4.72*10⁴

2.08*10⁶

7.23*10⁵

10

10.6

CAL4

1.93*10⁵

6.62*10⁴

1.53*10⁶

5.94*10⁵

25

25.2

CAL5

4.40*10⁵

1.46*10⁵

1.81*10⁶

6.40*10⁵

50

49.7

QC I

9.41*10⁴

3.48*10⁴

3.78*10⁶

1.52*10⁶

4

4.05

QC II

1.96*10⁵

6.86*10⁴

1.01*10⁶

4.05*10⁵

40

39.5

3° CALIBRATION CURVE R² = 0.9993 y = 0.00535x-0.000279

CAL 0

0.0

0.0

6.89*10⁵

2.41*10⁵

0.0

0.0

CAL1

2.69*10⁴

7.73*10³

1.94*10⁶

8.48*10⁵

2.5

2.65

CAL2

4.53*10⁴

1.49*10⁴

1.64*10⁶

5.64*10⁵

5

5.23

CAL3

1.09*10⁵

3.78*10⁴

2.00*10⁶

7.39*10⁵

10

10.3

CAL4

1.75*10⁵

5.69*10⁴

1.39*10⁶

5.06*10⁵

25

23.6

CAL5

3.68*10⁵

1.36*10⁵

1.43*10⁶

5.27*10⁵

50

50.6

QC I

5.61*10⁴

1.89*10⁴

2.79*10⁶

1.04*10⁵

4

3.82

QC II

2.76*10⁵

9.92*10⁴

1.17*10⁶

4.06*10⁵

40

44.2