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Table 1 MLD onset type by country

From: Understanding caregiver descriptions of initial signs and symptoms to improve diagnosis of metachromatic leukodystrophy

Onset type

MLD individuals, n (%)

Overall

US, n (%)

FR, n (%)

DE, n (%)

UK, n (%)

Total individuals

32 (100)*

10 (31.3)

11 (34.4)

6 (18.8)

5 (15.6)

Late infantile onset (age range ≤ 30 months)

20 (62.5)

6 (60.0)

7 (63.6)

4 (66.7)

3 (60.0)

Juvenile onset

 All juvenile (age range > 30 months to < 17 years)

11 (34.4)

3 (30.0)

4 (36.4)

2 (33.3)

2 (40.0)

 Early (age range > 30 months to < 7 years)

8 (25.0)

2 (20.0)

3 (27.3)

1 (16.7)

2 (40.0)

 Late (age range 7 to < 17 years)

3 (9.4)

1 (10.0)

1 (9.1)

1 (16.7)

0 (0.0)

  1. *Borderline late infantile/juvenile onset case not included in breakout of US sample onset types