Table 1 Comparison of head circumference and anthropometric classifications between neurofibromatosis 1 and control groups
NF1 (n = 84/100%) | CT (n = 84/100%) | p-value (NF1-CT) | NF1 Women (n = 55/100%) | CT Women (n = 55/100%) | p-value Woman (NF1-CT) | NF1 Men (n = 29/100%) | CT Men (n = 29/100%) | p-value Men (NF1-CT) | |
|---|---|---|---|---|---|---|---|---|---|
Macrocephaly | |||||||||
Yes | 49 (58.3%) | 15 (17.9%) | < 0.001a | 39 (70.9%) | 7 (12.7%) | < 0.001a | 10 (34.5%) | 8 (27.6%) | 0.791a |
No | 35 (41.7%) | 69 (82.1%) | 16 (29.1%) | 48 (87.3%) | 19 (65.5%) | 21 (72.4%) | |||
Stature | |||||||||
Normal | 55 (65.5%) | 80 (95.2%) | < 0.001a | 39 (70.9%) | 52 (94.5%) | 0.002a | 16 (55.2%) | 28 (96.6%) | < 0.001a |
Short Stature | 29 (34.5%) | 4 (4.8%) | 16 (29.1%) | 3 (5.5%) | 13 (44.8%) | 1 (3.4%) | |||
BMI (kg/m2) | |||||||||
Severe underweight | – | – | 0.036b | – | – | 0.317b | – | – | 0.041b |
Moderate underweight | – | – | – | – | – | – | |||
Mild underweight | – | 1 (1.2%) | – | 1 (1.8%) | – | – | |||
Normal | 42 (50.0%) | 35 (41.7%) | 25 (45.5%) | 26 (47.3%) | 17 (58.6%) | 9 (31%) | |||
Overweight | 30 (35.7%) | 23 (27.4%) | 21 (38.2%) | 11 (20.0%) | 9 (31.0%) | 12 (41.4%) | |||
Obesity Class I | 9 (10.7%) | 19 (22.6%) | 7 (12.7%) | 12 (21.8%) | 2 (6.9%) | 7 (24.1%) | |||
Obesity Class II | 3 (3.6%) | 4 (4.8%) | 2 (3.6%) | 3 (5.5%) | 1 (3.4%) | 1 (3.4%) | |||
Obesity Class III | – | 2 (2.4%) | – | 2 (3.6%) | – | – | |||
WHR | |||||||||
Normal WHR score | 49 (58.3%) | 30 (35.7%) | 0.004a | 36 (65.5%) | 20 (36.4%) | 0.004a | 13 (44.8%) | 8 (27.6%) | 0.581a |
High WHR score | 35 (41.7%) | 54 (64.3%) | 19 (34.5%) | 35 (63.6%) | 16 (55.2%) | 21 (72.4%) | |||