Table 4 Biochemical features
From: Hepatic glycogen storage diseases type 0, VI and IX: description of an italian cohort
Blood test | First visit | Last visit | p value | ||
|---|---|---|---|---|---|
Median | IQR | Median | IQR | ||
Hb (mg/dL) | 11.7 | 1.4 | 13.1 | 1.9 | < 0.001 |
Glucose (mg/dL) | 63 | 29.5 | 80 | 14.5 | < 0.05 |
INR | 1.1 | 0.1 | 1.1 | 0.1 | ns |
aPTT-ratio | 0.9 | 0.1 | 1 | 0.1 | ns |
Fibrinogen (mg/dL) | 289 | 56 | 286.5 | 89.3 | ns |
Triglycerides (mg/dL) | 132.5 | 106 | 91 | 55 | < 0.05 |
Total cholesterol (mg/dL) | 155 | 42 | 155 | 46.5 | ns |
HDL (mg/dL) | 27 | 9.3 | 37 | 15 | < 0.05 |
LDL (mg/dL) | 105 | 23.8 | 96 | 40 | ns |
Uric acid (mg/dL) | 4.7 | 1.5 | 4 | 1.6 | ns |
NEFA (μM/L) | 900.5 | 1020.5 | 745 | 472.5 | ns |
ALT (U/L) | 96 | 194.8 | 31 | 57 | < 0.05 |
AST (U/L) | 83 | 188.8 | 36 | 45 | < 0.01 |
CPK (U/L) | 88.5 | 45 | 101 | 41 | ns |
LDH (U/L) | 536 | 214 | 208 | 64.5 | < 0.001 |
CHE (U/L) | 7416 | 3482.5 | 8133 | 2293.5 | ns |
ALP (U/L) | 586 | 466.5 | 264 | 177 | < 0.001 |
GammaGT (U/L) | 20 | 25 | 16 | 9 | < 0.05 |
Alpha fetoprotein (ng/mL) | 3.5 | 7.7 | 1.5 | 2 | < 0.05 |
Basal insulin (µU/mL) | 1.1 | 1.2 | 4.7 | 7.3 | < 0.01 |
TSH (µU/mL) | 2.7 | 1.9 | 3.3 | 1.2 | ns |
FT4 (ng/dL) | 1.2 | 0.2 | 1.3 | 0.2 | ns |
IGF1 (ng/mL) | 29 | 45.4 | 97.9 | 106.3 | < 0.001 |
pH | 7.36 | 0.03 | 7.4 | 0.03 | ns |
HCO3 (mmol/L) | 20 | 3.5 | 22.7 | 1.8 | < 0.001 |
ABE (mmol/L) | -4.8 | 3.4 | -1.9 | 3 | < 0.001 |
Lactate (mmol/L) | 1.4 | 1 | 1.4 | 0.7 | ns |