A conceptual disease model for quality of life in mitochondrial disease

Table 3 Pearson correlations between the 5 levels of health concepts

	(1)	(2)	(3)	(4)	(5)	(6)	(7)	(8)	(9)	(10)	(11)	(12)	(13)	(14)
Demographics
(1) Age	1.00
(2) Gender	− 0.281**	1.00
(3) Education	0.324**	− 0.199	1.00
Biological and physiological
(4) Heteroplasmy urine	− 0.203	− 0.298*	0.005	1.00
(5) Heteroplasmy leucocytes	− 0.278*	0.273*	− 0.062	0.387**	1.00
(6) Disease manifestation (NMDAS)	0.021	− 0.253*	0.027	0.132	0.052	1.00
Symptom status
(7) Cognitive functioning (MOCA)	− 0.138	0.161	0.039	0.011	− 0.006	− 0.519**	1.00
(8) Fatigue (CIS F)	− 0.006	− 0.063	0.153	− 0.129	0.054	0.053	0.045	1.00
(9) Depression (BDI-PC)	− 0.132	− 0.053	− 0.122	− 0.015	0.014	0.123	− 0.074	0.342**	1.00
Functional health
(10) Societal participation (USERP F)	− 0.025	0.173	0.037	0.079	0.029	− 0.395**	0.593**	− 0.322**	− 0.304**	1.00
Health perceptions
(11) QoL physical functioning (SF36 PF)	− 0.184	0.146	− 0.163	0.316*	0.027	− 0.545**	0.313**	− 0.418**	− 0.141	0.411**	1.00
(12) QoL mental health (SF36 MH)	0.068	0.009	0.003	0.038	− 0.020	0.058	0.084	− 0.371**	− 0.813**	0.315**	0.039	1.00
(13) QoL social functioning (SF36 SF)	0.005	0.026	− 0.010	0.238	− 0.065	− 0.161	0.223*	− 0.453**	− 0.611**	0.437**	0.338**	0.723**	1.00
Overall QoL
(14) QoL general health (SF36 GH)	0.051	0.084	− 0.082	0.182	− 0.074	− 0.299**	0.089	− 0.578**	− 0.376**	0.386**	0.461**	0.403**	0.488**	1.00

ISSN: 1750-1172