A registry of achondroplasia: a 6-year experience from the Czechia and Slovak Republic

Table 1 Paternal age effect in ACH patients

Patient No	Father age	Median age	Difference	PAE
Patient No	(yrs)	(yrs)	(yrs)	PAE
1	51	33.9	17.1	Yes
2	50	34.1	15.9	Yes
3	49	34.2	14.8	Yes
4	47	33.9	13.1	Yes
5	47	34.1	12.9	Yes
6	45	33.1	11.9	Yes
7	44	32.4	11.6	Yes
8	44	32.6	11.4	Yes
9	45	33.6	11.4	Yes
10	42	33.1	8.9	Yes
11	39	32.4	6.6	Yes
12	39	33.4	5.6	Yes
13	37	32.4	4.6	Yes
14	38	33.6	4.4	Yes
15	37	32.8	4.2	Yes
16	37	32.8	4.2	Yes
17	38	34.1	3.9	Yes
18	36	32.8	3.2	Yes
19	37	34.1	2.9	Yes
20	36	33.4	2.6	Yes
21	36	34.1	1.9	No
22	35	33.6	1.4	No
23	34	33.1	0.9	No
24	35	34.1	0.9	No
25	35	34.2	0.8	No
26	34	33.4	0.6	No
27	34	33.9	0.1	No
28	33	33.1	− 0.1	No
29	33	33.1	− 0.1	No
30	34	34.1	− 0.1	No
31	34	34.3	− 0.3	No
32	33	33.4	− 0.4	No
33	32	32.6	− 0.6	No
34	32	33.1	− 1.1	No
35	32	33.9	− 1.9	No
36	31	33.1	− 2.1	No
37	31	33.9	− 2.9	No
38	30	33.4	− 3.4	No
39	28	31.7	− 3.7	No
40	28	31.7	− 3.7	No
41	29	33.1	− 4.1	No
42	28	33.6	− 5.6	No
43	28	33.6	− 5.6	No
44	28	33.9	− 5.9	No
45	26	32	− 6	No
46	26	34.2	− 8.2	No
		Mean difference ± SD: 2.65 ± 6.4 yrs

Paternal age effect (PAE) is presented as higher than two years above concurrent average age according to Goriely et al. [42], which correspond to 20 of 46 fathers of registry patients

ISSN: 1750-1172