Table 2 Comparison of data between baseline and 6 months after or at the cessation of the treatment
Baseline | After treatment | Change (95% CI) | p | |
|---|---|---|---|---|
(GM ± GSD) | (GM ± GSD) | Percentage change | ||
BNP (pg/mL) | ||||
FAS | 192.9 ± 1.72 | 188.8 ± 1.92 | − 2.1% (− 21.5 to 22.0) | 0.071 |
PPS | 191.7 ± 1.71 | 191.3 ± 1.88 | − 0.2% (− 15.7 to 18.1) | 0.036 |
hANP (pg/mL) | 189.7 ± 1.74, | 199.1 ± 2.19 | 5.0% (− 13.6 to 27.6) | 0.605 |
cTnT (mg/dL) | 0.026 ± 1.76 | 0.030 ± 1.88 | 14.6% (1.1 to 29.9) | 0.035 |
CK (IU/dL) | 269 ± 2.12 | 278 ± 2.41 | 3.5% (− 23.0 to 39.2) | 0.808 |
(mean ± SD) | (mean ± SD) | Change | ||
FS (%) | 9.02 ± 3.83% | 9.24 ± 4.06% | 0.22 (− 0.2 to 0.8) | 0.401 |
Pinch (kg) | 1.00 ± 1.74 | 0.78 ± 1.28 | − 0.29 (− 0.83 to 0.25) | 0.269 |
MDQoL-60 | ||||
Mental stability | 52.6 ± 16.1 | 55.8 ± 22.6 | 2.5 (− 5.7 to 10.7) | 0.523 |
ADL | 49.5 ± 29.8 | 53.6 ± 30.3 | − 0.8 (− 11.0 to 9.3) | 0.862 |
Environment | 71.6 ± 17.1 | 71.5 ± 14.1 | − 0.9 (− 7.3 to 5.4) | 0.763 |
Hope | 61.8 ± 22.7 | 55.5 ± 18.9 | − 6.2 (− 19.7 to 7.3) | 0.343 |
Activity | 42.4 ± 30.4 | 51.3 ± 28.1 | 7.0 (− 11.9 to 25.9) | 0.441 |
Sense of well-being | 63.2 ± 31.6 | 58.9 ± 25.3 | − 8.3 (− 26.6 to 9.9) | 0.344 |
Human relation | 63.2 ± 21.4 | 58.3 ± 23.4 | − 5.7 (− 16.9 to 5.5) | 0.297 |
Family | 72.6 ± 21.1 | 73.0 ± 20.6 | 1.0 (− 6.4 to 8.4) | 0.777 |
Sex | 64.2 ± 28.4 | 72.2 ± 20.3 | 9.4 (− 0.1 to 19.0) | 0.052 |
Respiration and bulbar function | 58.5 ± 18.8 | 61.7 ± 31.0 | 0.0 (− 13.7 to 13.7) | 1.000 |
Defecation | 64.7 ± 24.7 | 65.0 ± 35.4 | 0.8 (− 16.2 to 17.9) | 0.918 |
SF-12 | ||||
Physical function | 9.0 ± 14.1 | 5.6 ± 5.6 | − 4.7 (− 14.5 to 5.0) | 0.315 |
Role physical | 26.1 ± 18.9 | 29.8 ± 18.8 | 0.9 (− 11.0 to 12.7) | 0.880 |
Bodily pain | 49.4 ± 11.7 | 48.4 ± 12.1 | − 3.7 (− 10.2 to 2.7) | 0.238 |
General health | 51.6 ± 5.3 | 54.7 ± 7.7 | 3.1 (− 2.2 to 8.4) | 0.234 |
Vitality | 42.2 ± 11.1 | 45.1 ± 8.7 | 2.4 (− 3.7 to 8.6) | 0.413 |
Social function | 46.5 ± 12.1 | 43.6 ± 16.1 | − 5.3 (− 13.9 to 3.3) | 0.204 |
Role emotional | 49.5 ± 9.3 | 38.9 ± 14.8 | − 9.7 (− 17.5 to − 1.9) | 0.018 |
Mental health | 51.4 ± 6.9 | 47.8 ± 11.5 | − 3.6 (− 9.6 to 2.4) | 0.219 |