Fig. 3From: Identification of novel non-HFE mutations in Chinese patients with hereditary hemochromatosisAnalysis of SMAD6 and SMAD7 expression in UBE2O knockdown HCC cells. Western blot analysis of SMAD6, SMAD7, and pSmad1/5 expression in UBE2O knockdown Huh-7 and HepG2 cells showed that higher expression of Smad6 and Smad7 in UBE2O-knockdown HCC cells, and higher ratio of pSmad1/5/tSmad1 in Huh-7 cells, but lower ratio of pSmad1/5/tSmad1 in HepG2 cellsBack to article page