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Table 3 Risk of MODS and 30-day mortality according to triglyceride-fibrinogen groups

From: Fulfillment status of hypertriglyceridemia and hypofibrinogenemia in children with hemophagocytic lymphohistiocytosis and risks of multiple organ dysfunction syndrome and early mortality

Grouping methods

Triglyceride, mmol/L

Fibrinogen, mg/dL

MODS

30-day mortality

OR (95% CI)

P

OR (95% CI)

P

According to worst values during hospitalization

↑, ≥ 3.0

Normal

1 (Reference)

 

1 (Reference)

 

Normal

Normal

–

 

–

 

↑, ≥ 3.0

↓, ≤ 150

3.68 (1.18, 11.44)

0.0247

1.39 (0.35, 5.46)

0.6374

Normal

↓, ≤ 150

16.24 (3.71, 71.05)

0.0002

5.78 (1.34, 24.92)

0.0187

According to worst values within 72 h

↑, ≥ 3.0

Normal

1 (Reference)

 

–

 

Normal

Normal

2.85 (0.57, 14.33)

0.2032

1 (Reference)

 

↑, ≥ 3.0

↓, ≤ 150

4.88 (1.05, 22.57)

0.0425

1.67 (0.44, 6.24)

0.4485

Normal

↓, ≤ 150

7.39 (1.44, 37.88)

0.0165

4 (1.03, 15.53)

0.0452

  1. HLH, hemophagocytic lymphohistiocytosis; MODS, multiple organ dysfunction syndrome
  2. Values in bold are statistically significant (P < 0.05)