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Table 6 Summary of cardiovascular problems found in patients with MDS reported in the literature; NR = not reported

From: A brief history of MECP2 duplication syndrome: 20-years of clinical understanding

Feature

Males

n/N

Females

n/N

Total

n/N (%)

References

Septal defects

    

Atrial*

5/78

1/1

6/79 (8%)

[9, 32, 69, 77]

Ventricular

1/1

NR

1/1 (100%)

[67]

Vascular defects

    

Patent ductus arteriosus

9/46

1/1

10/47 (21%)

[9, 17, 24, 32, 40, 68]

Other

    

Cardiomegaly

4/87

NR

4/87 (5%)

[1, 5, 77]

Heart failure

5/21

NR

5/21 (24%)

[17, 48]

Myocarditis/pericarditis

1/5

1/1

2/6 (33%)

[1, 75]

  1. *Atrial septal defect (ASD) and patent foramen ovale (PFO)