Table 2 Summary of regression found in patients with MDS reported in the literature; NR = not reported

Developmental and/or intellectual regression

–

–

110/268 (41%)

[3, 4, 8, 10, 12, 36, 38, 41, 43, 48, 52, 53, 57, 61, 68, 71, 75, 77,78,79,80, 82,83,84, 113]

Regression of speech/ communication skills

8/17

5/8

13/25 (52%)

[3, 4, 10, 36, 38, 41, 43, 53, 68]

Regression of gross motor skills

–

–

36/93 (39%)

[3,4,5, 10, 12, 36, 38, 43, 53, 57, 61, 76, 77, 80]

Regression of purposeful hand use

13/59

1/8

14/67 (21%)

[4, 10, 12, 76]