Variables | Coefficients [95%CI] | |
---|---|---|
Univariable | Multivariable | |
Gender | ||
Male | Reference | Reference |
Female | 0.13 [0.07, 0.20]*** | 0.08 [0.01, 0.14]* |
Age | ||
18–25 | Reference | |
26–35 | 0.11 [− 0.17, 0.38] | |
36–45 | 0.08 [− 0.20, 0.35] | |
46–55 | 0.03 [− 0.25, 0.32] | |
56–65 | − 0.03 [− 0.35, 0.30] | |
66 + | 0.22 [− 0.50, 0.93] | − |
Birthplace | ||
Urban area | Reference | − |
Rural area | 0.04 [− 0.06, 0.14] | |
Others | − 0.19 [− 1.20, 0.82] | |
Monthly income | ||
< 5000 | Reference | Reference |
5000–10,000 | 0.15 [0.07, 0.23]*** | 0.11 [0.03, 0.18]** |
10,000–30,000 | 0.17 [0.07, 0.28]** | 0.14 [0.03, 0.25]* |
30,000–50,000 | 0.12 [− 0.54, 0.78] | − 0.03 [− 0.62, 0.56] |
> 50,000 | 0.06 [− 0.72, 0.85] | 0.21 [− 0.48, 0.91] |
Province | ||
Jiangsu | Reference | Reference |
Shandong | − 0.14 [− 0.25, − 0.03]* | − 0.10 [− 0.20, 0.00] |
Jiangxi | − 0.07 [− 0.17, 0.02] | − 0.04 [− 0.13, 0.05] |
Shanxi | − 0.16 [− 0.24, − 0.08]*** | − 0.10 [− 0.18, − 0.03]** |
Sichuan | − 0.01 [− 0.15, 0.13] | 0.02 [− 0.11, 0.15] |
Shannxi | − 0.14 [− 0.32, 0.04] | − 0.19 [− 0.36, − 0.01]* |
Education | ||
Secondary vocational school | Reference | Reference |
Three-year college | 1.14 [0.06, 2.22]* | 0.36 [− 0.64, 1.37] |
Bachelor | 1.42 [0.41, 2.43]** | 0.53 [− 0.41, 1.47] |
Master | 1.59 [0.58, 2.59]** | 0.63 [− 0.31, 1.57] |
Doctor/postdoc | 1.58 [0.57, 2.59]** | 0.61 [− 0.33, 1.56] |
Title | ||
Primary | Reference | − |
Middle | − 0.02 [− 0.10, 0.06] | |
Vice-senior | − 0.01 [− 0.10, 0.08] | |
Senior | 0.02 [− 0.09, 0.12] | |
None | 0.18 [− 0.20, 0.56] | |
Working years | ||
≤ 5 | Reference | Reference |
6–10 | − 0.04 [− 0.13, 0.05] | − 0.05 [− 0.13, 0.03] |
11–15 | − 0.07 [− 0.17, 0.03] | 0.00 [− 0.10, 0.09] |
16–20 | − 0.09 [− 0.19, 0.02] | − 0.05 [− 0.16, 0.05] |
21–25 | − 0.03 [− 0.14, 0.08] | 0.01 [− 0.09, 0.12] |
26–30 | − 0.07 [− 0.21, 0.06] | − 0.04 [− 0.17, 0.09] |
30 + | − 0.16 [− 0.32, − 0.01]* | − 0.18 [− 0.32, − 0.03]* |
Hospital class | ||
Primary hospital | Reference | Reference |
Secondary hospital | 0.38 [− 0.69, 1.44] | 0.19 [− 0.79, 1.17] |
Tertiary hospital | 1.11 [0.24, 1.99]* | 0.33 [− 0.48, 1.15] |
Specialty | ||
Internal medicine | Reference | Reference |
Anesthesiology | − 0.53 [− 0.83, − 0.23]** | − 0.45 [− 0.72, − 0.17]** |
Dermatology | 0.23 [− 0.01, 0.46] | 0.18 [− 0.04, 0.40] |
Emergency medicine | − 0.15 [− 0.34, 0.03] | − 0.11 [− 0.29, 0.06] |
Infectious disease | 0.04 [− 0.17, 0.26] | − 0.06 [− 0.26, 0.14] |
Intensive care unit | − 0.25 [− 0.44, − 0.06]* | − 0.20 [− 0.37, − 0.02]* |
Laboratory department | − 0.32 [− 1.31, 0.68] | − 0.13 [− 1.03, 0.77] |
Obstetrics and gynecology | − 0.26 [− 0.41, − 0.10]** | − 0.15 [− 0.30, − 0.01]* |
Oncology | − 0.28 [− 0.49, − 0.08]** | − 0.38 [− 0.56, − 0.19]*** |
Ophthalmology | − 0.03 [− 0.24, 0.18] | 0.00 [− 0.20, 0.20] |
Orthopedic surgery, medical cosmetology | − 0.26 [− 0.78, 0.26] | − 0.20 [− 0.66, 0.27] |
Otolaryngology | − 0.39 [− 0.68, − 0.10]** | − 0.46 [− 0.72, − 0.20]** |
Pain medicine | 0.18 [− 0.52, 0.89] | 0.36 [− 0.27, 0.99] |
Pathology | − 0.11 [− 0.72, 0.50] | − 0.44 [− 1.00, 0.11] |
Pediatrics | − 0.02 [− 0.13, 0.09] | 0.08 [− 0.02, 0.19] |
Psychiatry | − 0.51 [− 0.93, − 0.09]* | − 0.43 [− 0.81, − 0.05]* |
Radiology | − 0.36 [− 0.52, − 0.21]*** | − 0.16 [− 0.30, − 0.02]* |
Sports medicine, rehabilitation | − 0.45 [− 0.64, − 0.26]*** | − 0.16 [− 0.33, 0.02] |
Stomatology | − 0.47 [− 0.79, − 0.15]** | − 0.63 [− 0.93, − 0.34]*** |
Surgery | − 0.34 [− 0.44, − 0.24]*** | − 0.24 [− 0.34, − 0.14]*** |
Traditional Chinese medicine | − 0.50 [− 0.78, − 0.22]*** | − 0.19 [− 0.45, 0.06] |
Others | − 0.15 [− 0.32, 0.03] | − 0.06 [− 0.22, 0.10] |
Rare disease type | ||
Albinism | Reference | Reference |
Osteogenesis imperfecta | − 0.29 [− 0.45, − 0.13]*** | − 0.28 [− 0.44, − 0.12]** |
Homozygous hypercholesterolemia | − 0.27 [− 0.59, 0.05] | − 0.42 [− 0.74, − 0.10]* |
Duchenne muscular dystrophy | 0.11 [− 0.10, 0.31] | − 0.09 [− 0.30, 0.12] |
Multiple sclerosis | − 0.53 [− 0.64, − 0.42]*** | − 0.64 [− 0.75, − 0.52]*** |
Fabry disease | 0.26 [− 0.09, 0.62] | 0.07 [− 0.28, 0.42] |
Hepatolenticular degeneration | 0.38 [0.27, 0.48]*** | 0.25 [0.13, 0.36]*** |
Gaucher disease | 0.15 [− 0.25, 0.55] | − 0.04 [− 0.43, 0.36] |
Huntington disease | − 0.02 [− 0.41, 0.36] | − 0.03 [− 0.41, 0.35] |
Amyotrophic lateral sclerosis | − 0.22 [− 0.38, − 0.07]** | − 0.33 [− 0.49, − 0.17]*** |
Spinocerebellar ataxia | − 0.65 [− 1.06, − 0.24]** | − 0.69 [− 1.10, − 0.29]** |
Spinal muscular atrophy | − 0.39 [− 0.68, − 0.09]* | − 0.50 [− 0.80, − 0.21]** |
Spinal and bulbar muscular atrophy | − 1.04 [− 1.82, − 0.25]** | − 1.00 [− 1.78, − 0.23]* |
Tuberous sclerosis complex | 0.03 [− 0.24, 0.29] | − 0.10 [− 0.37, 0.16] |
Kallmann syndrome | 0.02 [− 0.29, 0.34] | − 0.14 [− 0.46, 0.17] |
Langerhans cell histiocytosis | 0.60 [0.44, 0.77]*** | 0.55 [0.38, 0.72]*** |
Lymphangioleiomyomatosis | − 0.12 [− 0.34, 0.10] | − 0.28 [− 0.50, − 0.06]* |
Marfan syndrome | 0.07 [− 0.06, 0.19] | 0.00 [− 0.13, 0.12] |
Niemann-Pick disease | 0.71 [0.26, 1.17]** | 0.64 [0.18, 1.09]** |
Mucopolysaccharidosis | 0.55 [− 0.10, 1.19] | 0.31 [− 0.32, 0.95] |
Prader–Willi syndrome | − 0.53 [− 0.77, − 0.29]*** | − 0.79 [− 1.04, − 0.55]*** |
General myathenic gravis | 0.08 [− 0.07, 0.22] | 0.05 [− 0.10, 0.20] |
Neuromyelitis optica | 0.20 [0.02, 0.38]* | 0.03 [− 0.16, 0.21] |
Type II glycogen storage disease | − 0.45 [− 1.36, 0.45] | − 0.66 [− 1.55, 0.23] |
Idiopathic hypogonadotropic hypogonadism | − 0.09 [− 0.33, 0.14] | − 0.28 [− 0.52, − 0.05]* |
Idiopathic pulmonary arterial hypertension | 0.48 [0.34, 0.62]*** | 0.33 [0.19, 0.48]*** |
Systemic sclerosis | 0.50 [0.36, 0.65]*** | 0.32 [0.17, 0.47]*** |
Congenital adrenal hypoplasia | 0.24 [− 0.01, 0.48] | 0.01 [− 0.23, 0.26] |
Hemophilia | 0.64 [0.52, 0.76]*** | 0.58 [0.46, 0.69]*** |
Hereditary epidermolysis bullosa | − 0.35 [− 0.69, − 0.02]* | − 0.52 [− 0.85, − 0.19]** |
Severe myoclonic epilepsy in infaricy | − 0.45 [− 1.10, 0.19] | − 0.54 [− 1.18, 0.09] |
Hyperphenylalaninemia | 0.01 [− 0.69, 0.72] | − 0.19 [− 0.88, 0.50] |
Phenylketonuria | − 1.13 [− 1.32, − 0.93]*** | − 1.18 [− 1.38, − 0.97]*** |
Tetrahydrobiopterin deficiency | − 0.79 [− 2.35, 0.78] | − 1.05 [− 2.59, 0.48] |