Table 1 Presentation of oral complications among NF1 patients and NF1- controls
From: Age-dependent oral manifestations of neurofibromatosis type 1: a case–control study
Index | Age subgroups | Mean of NF1- controls | Mean of NF1 + cases | Mean difference (95% CI) = values of NF1 + —that of NF1- | P value |
|---|---|---|---|---|---|
Salivary flow rate | < 20 | 0.340 | 0.335 | − 0.005 (− 0.019–0.0092) | 0.45 |
Salivary flow rate | 21–40 | 0.321 | 0.293 | − 0.029 (− 0.047– − 0.011) | 0.005 |
Salivary flow rate | > 40 | 0.292 | 0.173 | − 0.12 (− 0.15– − 0.09) | < 0.0001 |
Amylase activity | < 20 | 0.387 | 0.374 | − 0.013 (− 0.03–0.0083) | 0.15 |
Amylase activity | 21–40 | 0.377 | 0.323 | − 0.053 (− 0.075– − 0.033) | 0.0008 |
Amylase activity | > 40 | 0.360 | 0.292 | − 0.068 (− 0.089– − 0.047) | < 0.0001 |
Salivary pH value | < 20 | 7.04 | 7.08 | 0.032 (− 0.068–0.13) | 0.49 |
Salivary pH value | 21–40 | 7.10 | 7.80 | 0.70 (0.46–0.94) | < 0.0001 |
Salivary pH value | > 40 | 7.17 | 8.27 | 1.10 (0.911.27) | < 0.0001 |
PI | < 20 | 0.49 | 0.66 | 0.16 (− 0.016–0.35) | 0.07 |
PI | 21–40 | 1.46 | 3.70 | 2.25 (0.69–3.80) | 0. 009 |
PI | > 40 | 4.80 | 6.53 | 1.73 (0.16–3.31) | 0.03 |
DMFT score | < 20 | 1.86 | 1.25 | − 0.61 (− 2.80–1.59) | 0.55 |
DMFT score | 21–40 | 4.62 | 9.5 | 4.88 (0.33–9.41) | 0.04 |
DMFT score | > 40 | 7.71 | 22.67 | 14.95 (12.44–17.47) | < 0.0001 |