Table 6 The comparison of studies in prevalence of genetic variants identified in CHD fetuses by CMA
Study | Platform | Number | Total chromosomal abnormalities | Aneuploidies | Partial Aneuploidies | pCNVs | lpCNVs | Vous |
|---|---|---|---|---|---|---|---|---|
Song et al. 2018 [18] | Affymetrix Cytoscan 750 k array | 207 | 35 (16.9%) | 17 (8.2%) | - | 13 (6.3%) | 5 (2.4%) | 14 (6.8%) |
Luo et al. 2018 [19] | Illumina HumanCytoSNP-12 v2.1 BeadChip | 362 | 140 (38.7%) | 111 (30.7%) | 10 (2.8%) | 17 (4.7%) | 2 (0.6%) | - |
Zhu et al. 2016 [20] | AffymetrixCytoScanplatform | 115 | 21 (18.3%) | 6 (5.2%) | 2 (1.7%) | 11 (9.6%) | 2 (1.7%) | - |
Wang et al. 2017 [21] | Illumina HumanCytoSNP-12 v2.1 BeadChip | 602 | 133 (22.1%) | 65 (10.8%) | 20 (3.3%) | 40 (6.7%) | 8 (1.3%) | 36 (6.0%) |
Liao et al. 2014 [22] | Affymetrix CytoScan HD arrays | 99 | 19 (19.2%) | excluded by CK | excluded by CK | 19 (19.2%) | - | 13 (13.1%) |
Our study | Affymetrix Cytoscan 750 k array | 200 | 49 (24.5%) | 23 (11.5%) | - | 20 (10.0%) | 6 (3.0%) | 8 (4%) |