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Table 2 CCM parameters in controls and patients with ALS

From: Small fiber neuropathy for assessment of disease severity in amyotrophic lateral sclerosis: corneal confocal microscopy findings

 

Control, N = 64

ALS, N = 66

P value

Inferior whorl area

Corneal Nerve

IWL (mm/mm2)

19.96 (3.05)

18.33 (3.14)

0.014

Dendritic Cell

IWDC (/mm2)

20.02 (9.09)

36.83 (31.77)

0.020

Peripheral area

Corneal Nerve

CNFL (mm/mm2)

19.52 (2.50)

17.80 (3.79)

0.017

CNFD (/mm2)

38.13 (8.23)

33.90 (7.64)

0.011

CNBD (/mm2)

50.07 (14.56)

58.40 (22.70)

0.040

Dendritic Cell

CDC (/mm2)

13.55 (8.77)

27.75 (27.55)

0.019

  1. Data are presented as mean (SD) values
  2. CCM, corneal confocal microscopy; ALS, amyotrophic lateral sclerosis; IWL, corneal nerve length in the inferior whorl area; IWDC, dendritic cell density in the inferior whorl area; CNFL, corneal nerve fiber length in the peripheral area; CNFD, corneal nerve fiber density in the peripheral area; CNBD, corneal nerve branch density in the peripheral area; CDC, corneal dendritic cell density in the peripheral area