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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Sebelipase alfa enzyme replacement therapy in Wolman disease: a nationwide cohort with up to ten years of follow-up

Fig. 2

Long-term follow-up of cholesterol fractions, triglycerides and fat-soluble vitamin levels in five Wolman disease (WD) patients treated with sebelipase alfa. A Total cholesterol, B low-density lipoprotein cholesterol (LDL-C), C high-density lipoprotein cholesterol (HDL-C), D triglycerides, E vitamin A, F vitamin D, G vitamin E levels measured in Patients 1–5 (P#1–P#5), before (black) and under (orange) enzyme replacement therapy (ERT). The grey zones and the dotted lines represent the normal values and their limits, respectively. Mann–Whitney test pre versus post, median ± interquartile range, n.s. not significant

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