Table 3 Symptoms mentioned in concept elicitation interviews and their disturbance ratings
Symptom | Total patients mentioning (n = 23) (%) | Patients mentioning concept (spontaneous) | Patients mentioning concept (probed) | Average disturbance rating* |
|---|---|---|---|---|
Abdominal pain | 22 (96%) | 22 | 0 | 8.3 |
Nausea | 21 (91%) | 16 | 5 | 7.1 |
Diarrhea | 21 (91%) | 14 | 7 | 5.4 |
Fatigue | 19 (83%) | 10 | 9 | 7.3 |
Vomiting | 16 (70%) | 16 | 0 | 5.9 |
Heartburn | 16 (70%) | 7 | 9 | 5.6 |
Bloating | 16 (70%) | 9 | 7 | 4.8 |
Lack of appetite | 16 (70%) | 5 | 11 | 4.4 |
Early satiety | 15 (65%) | 5 | 10 | 5.6 |
Constipation | 13 (57%) | 10 | 3 | 5.0 |
Gassiness/burping | 14 (61%) | 7 | 7 | 5.5 |
More frequent bowel movements | 13 (57%) | 5 | 8 | 5.8 |
Feeling hungry | 13 (57%) | 3 | 10 | 5.6 |
Flank pain | 9 (39%) | 3 | 6 | 6.5 |
Muscle pain | 8 (35%) | 2 | 6 | 5.0 |
Larger bowel movements | 7 (30%) | 3 | 4 | 5.2 |
Pain/discomfort in upper abdomen | 7 (30%) | 4 | 3 | 6.8 |
Acid reflux | 9 (39%) | 7 | 2 | 7.2 |
Food aversions | 5 (22%) | 3 | 2 | 7.4 |
Chest pain | 6 (26%) | 2 | 4 | 4.7 |
Joint pain | 6 (26%) | 1 | 5 | 7.3 |
Stiff fingers, toes, and neck | 5 (22%) | 2 | 3 | 5.9 |
Dry mouth | 4 (17%) | 2 | 2 | 3.7 |
Trouble swallowing | 2 (9%) | 2 | 0 | 7.5 |
Heightened sense of smell | 2 (9%) | 2 | 0 | 3.5 |
Failure to thrive/growth retardation | 2 (9%) | 1 | 1 | 9.5 |
Dehydration | 2 (9%) | 2 | 0 | 3.0 |
Disorientation | 1 (4%) | 1 | 0 | 6.0 |
Numb fingers/toes | 2 (9%) | 1 | 1 | 7.5 |
Hot flashes | 2 (9%) | 1 | 1 | 1.7 |
Food stuck in esophagus | 2 (9%) | 1 | 1 | Not reported |
Choking | 1 (4%) | 1 | 0 | Not reported |
Trouble digesting | 1 (4%) | 1 | 0 | Not reported |